Abstract: In this paper,by the load-unload response ratio theory,the variational characteristics of the load-unload response ratio before and after the Ms6.2 earthquake have been studied.The result showed that there was an obvious anomaly of the loas-unload response ratio before the earthquake.The influence factors to the anomaly include time,amplitude,selected region,magnitude lower limit,and seismotectonics also.The relationship between anomaly and earthquake showed that the earthquake occurred when the anomaly raised,turned and retumned to normal.The time of the anomly lasted half a year to six years.