Abstract: The Jiyang Depression is an important distribution area of helium-rich natural gas in Shandong, which has favorable conditions for helium resource accumulation. The wide-field electromagnetic method was used to detect the helium enrichment area in Jiyang Depression, and the "Integrated System for the Processing and Interpretation of Electromagnetic Exploration Data" was used to process and invert the raw data of the wide-field electromagnetic method to obtain the distribution characteristics of the lithological resistivity of the strata within 3km underground. The electrical relationship between the wide-field apparent resistivity and the cover layers and storage layers in the test area was established, and the relationship between the deep fault structure and the helium migration channel was also revealed. On the basis of comprehensive research, the distribution and thickness of the main helium storage layers in the area, such as the Guantao Formation, the Dongying Formation, the first member of the Shahejie Formation and the third member of the Shahejie Formation, as well as the helium migration channels and structural traps, have been basically ascertained．Through this work, a wide-field electromagnetic data acquisition and processing method suitable for helium exploration in the Jiyang Depression has been formed, which enriches the research results of helium detection in Jiyang Depression and provides geophysical parameters for further promoting helium exploration in Jiyang Depression.