Abstract: The article describes the overall architecture of the Guangxi earthquake emergency video conference system from the aspects of system integration and hardware configuration. Through its application in Jingxi M_S5.2 earthquake, the shortcomings of the networking mode and the group meeting mode in the post-earthquake emergency process are proposed. The causes of the problems such as unclear image, out of control signal transmission, lack of integration practicability etc. are analyzed and corresponding solutions are puts forward. The timely improvement of the problems improves the service quality of the video conference system, and improves the ability of regional linkage and collaborative emergency response after the earthquake.