Abstract: There are a series of NW transverse faults along the eastern margin of the Hefei basin. We analyzed and sampled the NW fault profiles in the bedrock outcropping area and constructed shallow seismic lines across one of the faults. Based on the Quaternary thickness and sedimentary characteristics of this area, geological interpretation of shallow seismic profile is made. The profile characteristics and the ESR dating of fault gouges indicate that the NW faults have been active in the Middle Pleistocene. The Quaternary activity of the NW transverse faults in the eastern margin of the Hefei basin are related to the neotectonic environment in the area. Although the results of gouge dating show that the faults have been active in the Middle Pleistocene, theirs activity are not strong.