Abstract: According to the principle of the multi-component borehole strain observation, the interferences of water work pumping, calibration, repairing of equipments in the same cabinet, digital acquisition system restarting, abrupt change of weather and thunder to the multi-component borehole strain observation are analyzed.Analysis shows that the fluctuations in borehole strain observations are basically consistent with the interferences;So that, the water works pumping, repairing equipment in the same cabinet, thunder and other weather changes lead to the interferences to the multi-component borehole observations to a certain degree.