Abstract: By collating the seismic phase observation reports of Anhui Digital Seismic Network of China Earthquake Administration from 2013 to 2022, the characteristics of wave velocity ratio change in Anhui and its adjacent areas are analyzed and studied by using the multi-station Wadati method. It is found that Huoshan window plays an important role in stress regulation and energy release in Anhui area. In addition, the change of wave velocity ratio in central Anhui is basically consistent with the change of the whole wave velocity ratio in the study area, and the spatial wave velocity ratio increases from north to south. According to the monthly sliding average of the wave velocity ratio results, it is found that the study area has obvious periodic change characteristics of the wave velocity ratio, and Anhui and its surrounding areas are prone to M_S3.0 earthquakes during the relatively obvious decline period of wave velocity ratio.