Abstract: The paper takes the overall national security concept of "Promoting the Modernization of National Security System and Capabilities" as the guiding ideology, and takes "Safety First, Prevention First" and "Establishing A Major Safety and Emergency Framework" as the fundamental direction and guide of earthquake prevention and disaster reduction work in the new era and new journey. Summarize the current development status of earthquake warning work in China, deeply analyze the opportunities and challenges faced by the earthquake warning work in the new era and new journey, and explore new ideas and methods for the construction of the earthquake warning mechanism in the future new era and new journey.