Abstract: In this paper, we apply the spring-block model controlled by the velocity and state depended frictional constitutive relation to research the effect of interaction between two fault segments on their motions. In order to research the effect of interaction between Kusai Lake and Xidatan segment of East Kunlun fault, we use two blocks connected by spring to simulate these two fault segments.Through the dynamical analysis, we get the differential equations to depict fault segment motion.Numerically solving the fault motion equations, we have the parameters of fault motion and determine the recurrence of strong earthquake.With the help of dislocation model research achievements of previous scholar and the data of paleo-earthquakes, we determine the related parameters of spring block model.Through the simulation, we find that the interaction between Kusai Lake and Xidatan fault segment has no regularity effect on recurrent period of earthquake and sliding displacement when earthquake happen, but the strong interaction will make the quick slip velocity of fault and the weak interaction will make the slow one.