Abstract: The regional comprehensive seismic data base system introduced in this paper, by taking a certain technical measures,not only has the modular program structure of an ordinary applied software, has an all-purpose property and a strong portability,has a simple design, a friendly user's medium and strong fault freedom and error correcting property, but also has a memory (intelligent) input modulor which can be used for a large amount of input of seismic data and by which the working efficiency has doubled;based on setting up sub data baese in terms of stations and items, using isodivision algorithm further realized fast retrieve function, which can raise the inquiry speed several folds either for the data of equal time interval sequence or unequal time interval sequence.These methods not only can be used to seismic data mana gement but also can be used to the data management and inquiry of a large amount of similar data in other areas.