Abstract: Based on the UAV remote sensing high resolution orthophoto image and the oblique aerial photography, the disaster characteristics of the Guangxi Jingxi M_S5.2 earthquake was analyzed using remote sensing interpretation. Through image data processing and identification of earthquake damage information, combined with the ground disaster investigation on the damage of buildings in the seismic center of FuliTun, Huali village, the quantitative evaluation method of “seismic damage index” is used to quickly determine the seismic intensity in the seismic center. The results show that the UAV remote sensing technology is one of the effective methods to improve the rapid investigation and assessment of earthquake disasters. 10 earthquake damage information of buildings can be quickly identified from remote sensing images. Due to the limitations of remote sensing technology, it is impossible to identify the damage inside the building. Therefore, a comprehensive analysis and assessment should be carried out in combination with the ground field investigation. The seismic intensity in the remote sensing is Ⅵ degrees. By this method, the quantitative transformation model or appropriate modification of remote sensing earthquake damage and ground survey earthquake damage information is established. The study may provide seismic intensity remote sensing rapid assessment services for the Guangxi region.