Abstract: The selection of seismic waves in time history analysis is related to the accuracy of seismic analysis results. Based on the standard response spectrum, wave selection analysis is carried out to study the characteristics and error size of seismic waves selected under different wave selection control indexes in time domain and frequency domain, and engineering verification is carried out. The results show that the characteristics of the ground motion selected by the wave selection method with the fitted response spectrum vary greatly in the time and frequency domain, which is the main reason for the large difference in the structural response in the time history analysis method, and the selection of more strict control indexes cannot effectively reduce the difference between the selected time-frequency non-stationary ground motion