Abstract: The seismic hazard prediction for single building of 182 multifloor brick buildings in Weifang area of Shandong Province has been made one by one by the expert system of seismic hazard prediction for multi-floor brick buildings.Based on this,the statistics and analysis have been made for the seismic vulnerabi lity characteristics of multi-floor brick buildings in the area and a preliminary study of seismic hazard prediction has been made.The vulnerability matrix,the loss parameter matrix of various damage grades and the relative loss prediction corresponding to different seismic intensities of this ikind of buildings are given,which has provided a scientific basis for further carrying out seismic hazard prediction and taking countermeasure for earthquake prevention and hazard reduction.